Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition

The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 ACP/TiO2/ /ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there no significant decrease the survival healthy cells exposed to samples without lactate, while an increase number viable sample containing ChOL. These findings show improved proliferation, differentiation viability ChOL-containing sample, which makes ACP/TiO2/ChOL coating good candidate for applications medicine stomatology.